PREPARATION OF 6-UNSUBSTITUTED 3,4-DIHYDROPIRIMIDIN-2(1<i>Н</i>)-ONES AND 2-ARYLAMINOPYRIMIDINES
DOI:
https://doi.org/10.1007/1060Keywords:
2-oxo-1, 2, 3, 4-tetrahydropyrimidines, 2-dihydropyrimidines, 2-chloropyrimidines, 2-(arylamino)pyrimidines, Biginelli reactionAbstract
A series of new 6-unsubstituted 3,4-dihydropyrimidin-2(1H)-ones have been obtained from methyl propiolate, as well as from methyl 3-diethylaminoacrylate, using the Biginelli reaction. By subsequent oxidation of the pyrimidine reing, clorination of the 2-oxo group, and substitution of the chlorine atom by an aromatic amine they have been converted into heretofore unknown 2-(arylamino)pyrimidines. 2-Oxo- and 2-(arylamino)pyrimidine-5-carboxylic acids also were obtained.
How to Cite
Terentjeva, S.; Muceniece, D.; Lusis, V. Chem. Heterocycl. Compd. 2014, 49, 1757. [Khim. Geterotsikl. Soedin. 2013, 1896.]
For this article in the English edition see DOI 10.1007/s10593-014-1428-0
