ETHYL 5-AMINO-3-OXO-1,2-DIHYDRO-1<i>H</i>-PYRAZOLE-1-CARBOXYLATE IN THE SELECTIVE SYNTHESIS OF PARTIALLY HYDROGENATED PYRAZOLO[3,4-<i>b</i>]PYRIDIN-3-ONES

Authors

  • П. С. Лебедь Institute of Organic Chemistry, Ukraine National Academy of Sciences
  • Н. Г. Мозговая Institute of Organic Chemistry, Ukraine National Academy of Sciences
  • П. О. Кос Institute of Organic Chemistry, Ukraine National Academy of Sciences
  • М. В. Вовк Institute of Organic Chemistry, Ukraine National Academy of Sciences

DOI:

https://doi.org/10.1007/1269

Keywords:

5-amino-1-ethoxycarbonyl-1, 2-dihydro-1H-pyrazol-3-one, 5-aminopyrazol-3-one, 1, 3-dicarbonyl compounds, pyrazolo[3, 4-b]pyridin-3-ones, cyclocondensation

Abstract

Ethyl 5-amino-3-oxo-1,2-dihydro-1H-pyrazole-1-carboxylate undergoes selective cyclocondensation with 1,3-dicarbonyl compounds or their synthetic equivalents to give ethyl 3-oxo-1,2-dihydro-pyrazolo[3,4-b]pyridine-1-carboxylates which are readily converted to their 1-unsubstituted analogs.

Authors: P. S. Lebed', N. G. Mozgovaya, P. O. Kos, and M. V. Vovk.

English translation in Chemistry of Heterocyclic Compounds, 2012, 48 (2), pp 368-371

http://link.springer.com/article/10.1007/s10593-012-0999-x

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Published

2013-12-02

Issue

No. 2 (2012)

Section

Original Papers