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MULTICOMPONENT SYNTHESIS OF THE MEDICINALLY IMPORTANT PYRROLO[2,3-d]PYRIMIDINE SCAFFOLD

R. Dasari, A. Kornienko
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Abstract


Multicomponent reactions are emerging as a powerful tool in the synthesis of heterocyclic privileged medicinal scaffolds. This highlight describes a recently developed approach to the construction of the medicinally important pyrrolo[2,3-d]pyrimidine scaffold using a one-pot synthesis from commercially available starting materials via novel multicomponent reactions.

How to Cite
Dasari, R.; Kornienko, A. Chem. Heterocycl. Compd. 2014, 50, 139. [Khim. Geterotsikl. Soedin. 2014, 160.]

For this article in the English edition see DOI 10.1007/s10593-014-1456-9


Keywords


multicomponent reactions; drug discovery; heterocycle; privileged scaffold; 7-deazapurines

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