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AN EFFECTIVE ACTIVATION OF PALLADIUM PHOSPHINE COMPLEXES IN AQUEOUS PHASE REACTIONS OF HETEROAROMATIC BORONIC ACIDS WITH ARYL HALIDES

Н. А. Бумагин, И. С. Веселов, Д. С. Белов
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Abstract


We have developed a simple and effective method for the activation of palladium phosphine complexes in the Suzuki reaction (TON up to 9800, TOF up to 58800 h-1) by selecting an aqueous reaction medium instead of organic solvents. This method was elaborated for a high yield synthesis of heteroaromatic biaryls with furyl and thienyl groups.

How to Cite
Bumagin, N. A.; Veselov, I. S.; Belov, D. S. Chem. Heterocycl. Compd. 2014, 50, 19. [Khim. Geterotsikl. Soedin. 2014, 24.]

For this article in the English edition see DOI 10.1007/s10593-014-1443-1


Keywords


heteroaromatic boronic acids; palladium phosphine complexes; water; activation; Suzuki reaction

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