REACTION OF METHYL 3-[(DIMETHYLAMINO)METHYLIDENE]-6-FLUORO-4-OXO-3,4-DIHYDROCHROMAN-2-CARBOXYLATE WITH PRIMARY AND SECONDARY AMINES

Authors

  • А. И. Кисель Taras Shevchenko Kyiv National University
  • В. С. Москвина Taras Shevchenko Kyiv National University
  • А. В. Туров Taras Shevchenko Kyiv National University
  • З. В. Войтенко Taras Shevchenko Kyiv National University
  • В. П. Хиля Taras Shevchenko Kyiv National University

DOI:

https://doi.org/10.1007/1410

Keywords:

3-aminomethylidenechroman-4-one, primary and secondary amines, chroman, bioisosteric displacements

Abstract

A method was developed for substitution of the dimethylamino group by bioisosteric fragments by the action of various primary and secondary amines on methyl 3-[(dimethylamino)methylidene]-6-fluoro-4-oxo-3,4-dihydrochroman-2-carboxylate.

Authors: A. I. Kysil, V. S. Moskvina, A. V. Turov, Z. V. Voitenko, and V. P. Khilya.

English translation in Chemistry of Heterocyclic Compounds, 2011, 47 (8), pp 946-952

http://link.springer.com/article/10.1007/s10593-011-0859-0

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Published

2013-12-18

Issue

No. 8 (2011)

Section

Original Papers