Open Access Open Access  Restricted Access Subscription Access

INTERACTION OF 2-ARYL-4-CYANO-1,3-OXAZOL-5-SULFONYLCHLORIDES WITH 5-AMINO-3R-1H-PYRAZOLES AND 5-AMINO-1H-1,2,4-TRIAZOLE

А. Н. Корниенко, С. Г. Пильо, А. П. Козаченко, В. М. Прокопенко, Э. Б. Русанов, В. С. Броварец
Cover Image

Abstract


By interaction of 2-aryl-4-cyano-1,3-oxazole-5-sulfonylchlorides with 5-amino-3R-1Н-pyrozoles and 5-amino-1Н-1,2,4-triazole were obtained 5-[(3-R-5-Amino-1H-pyrazol-1-yl)sulfonyl]-2-aryl-1,3-oxazol-4-carbonitriles and 5-[(5-amino-1H-1,2,4-triazol-1-yl)sulfonyl]-2-aryl-1,3-oxazol-4-carbonitriles, which under action of sodium hydride eliminate sulfur dioxide and undergo cyclocondensation into new heterocyclic systems – oxazolo[5,4-d]pyrazolo[1,5-a]pyrimidine and oxazolo[5,4-d][1,2,4]triazolo[1,5-a]pyrimidine.

How to Cite
Kornienko, A. N.; Pil'o, S. G.; Kozachenko, A. P.; Prokopenko, V. M.; Rusanov, E. B.; Brovarets, V. S. Chem. Heterocycl. Compd. 2014, 50, 76. [Khim. Geterotsikl. Soedin. 2014, 84.]

For this article in the English edition see DOI 10.1007/s10593-014-1450-2


Keywords


5-amino-1Н-pyrazole; 5-amino-1Н-1,2,4-triazole; sodium hydride; [1,3]oxazolo[5,4-d]pyrazolo[1,5-a]pyrimidine-9-amine; [1,3]oxazolo[5,4-d][1,2,4]triazolo[1,5-a]pyrimidine-9-amine; 4-cyano-1,3-oxazole-5-sulfonyl chloride

Full Text: PDF (Russian) Supplementary File(s): None


 

 

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv