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CYCLO(L-PRO-L-TYR), THE FUNGICIDE ISOLATED FROM LYSOBACTER CAPSICI AZ78: A STRUCTURE–ACTIVITY RELATIONSHIPS STUDY

A. Cimmino, G. Puopolo, M. Perazzolli, A. Andolfi, D. Melck, I. Pertot, A. Evidente
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Abstract


Four hemisynthetic derivatives were prepared from maculosin (cyclo(L-Pro-L-Tyr)), isolated from Lysobacter capsici AZ78 and having anti-oomycete activity against some fungi pathogenic crop plants. A very strong antifungal activity was showed by the azido derivatives of maculosin, which could have pratical application in agriculture as safe fungicide.

How to Cite
Cimmino, A.; Puopolo, G.; Perazzolli, M.; Andolfi, A.; Melck, D.; Pertot, I.; Evidente, A. Chem. Heterocycl. Compd. 2014, 50, 290. [Khim. Geterotsikl. Soedin. 2014, 317.]

For this article in the English edition see DOI 10.1007/s10593-014-1475-6


Keywords


Lysobacter capsici; cyclo(L-Pro-L-Tyr); anti-oomycete activity; SAR

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