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SYNTHESIS OF 2,5-DIHYDROISOTHIAZOLE DERIVATIVES. 2. 3-ARYL(HETARYL)-SUBSTITUTED 2-ALKYL-5-ARYLIMINO-2,5-DIHYDROISOTHIAZOLES

И. Скрастиня, А. Баран, Д. Муцениеце, Ю. Попелис
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Abstract


A series of new 2-alkyl-5-arylimino-2,5-dihydroisothiazoles, substituted at position 3 with aryl and hetaryl groups and not substituted at position 4 was prepared by oxidative cyclization of N-arylamides of 3-alkylaminoprop-2-enethioic acids. The formation of the starting thioanilides was investigated by reacting the respective N-alkylimines of acetophenones with isothiocyanates. The main by-products were identified and characterized.

How to Cite
Skrastiņa, I.; Baran, A.; Muceniece, D.; Popelis, J. Chem. Heterocycl. Compd. 2014, 50, 87. [Khim. Geterotsikl. Soedin. 2014, 96.]

For this article in the English edition see DOI 10.1007/s10593-014-1451-1


Keywords


2-alkyl-3-aryl(hetaryl)-5-arylimino-2,5-dihydroisothiazole; N-arylamides of 3-alkylamino-3 aryl(hetaryl)prop-2-enethioic acid; oxidative cyclization

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