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А. О. Гуренко, Б. М. Хутова, С. В. Ключко, А. Н. Василенко, В. С. Броварец
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Studies have been conducted of the reactions of 7-phenyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4‑one with alkyl halides and formaldehyde, that occurred with retention of the pyrazolotriazine structure. Ethyl 2-(4-oxo-7-phenyl-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)acetate was prepared by the reaction of 7-phenyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one with ethyl chloroacetate. It was used to synthesize the corresponding hydrazide with the aim of introducing  the pyrazole or 1,3,4-oxadiazole fragments in the side chain of a bicyclic system.

How to Cite
Gurenko, A. O.; Khutova, B. M.; Klyuchko, S. V.; Vasilenko, A. N.; Brovarets, V. S. Chem. Heterocycl. Compd. 2014, 50, 528. [Khim. Geterotsikl. Soedin. 2014, 577.]

For this article in the English edition see DOI 10.1007/s10593-014-1503-6


pyrazole; pyrazolotriazine; 1,3,4-oxadiazole; hydrazide; alkylation

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