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SYNTHESIS OF 3-(ALK-2-YN-1-YL)-1,3-OXAZOLIDINES USING COPPER-CONTAINING CATALYSTS

Г. Р. Хабибуллина, В. М. Яныбин, А. Г. Ибрагимов, У. М. Джемилев
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Abstract


A selective method for the synthesis of 3-(alk-2-yn-1-yl)-1,3-oxazolidines has been developed by the reaction of bis(oxazolidin-3-yl)methanes with terminal acetylenes with copper-containing catalysts. The reaction of terminal acetylenes with optically active bis((4R)-4-ethyl-1,3-oxazolidin-yl)methane led to the formation of (4R)-3-(2-alkynyl)-4-ethyl-1,3-oxazolidines.

How to Cite
Khabibullina, G. P.; Yanybin, V. M.; Ibragimov, A. G.; Dzhemilev, U. M. Chem. Heterocycl. Compd. 2014, 50, 726. [Khim. Geterotsikl. Soedin. 2014, 788.]

For this article in the English edition see DOI 10.1007/s10593-014-1527-y


Keywords


3-(alk-2-yn-1-yl)-1,3-oxazolidines; bis(1,3-oxazolidin-3-yl)methane; 3,8-dioxa-1,6-diazabicyclo[4.4.1]undecane; terminal acetylenes; catalysis

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