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REGIOSELECTIVE SYNTHESIS OF PYRIDIN-2-ONE DERIVATIVES BASED ON ETHYL(1-PHENYLETHYLIDENE)CYANOACETATE AND CYANOACETAMIDES

С. Р. Фефелова, Д. А. Красников, В. Д. Дяченко, А. Д. Дяченко
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Abstract


Ethyl(1-phenylethylidene)cyanoacetate reacted with cyanoacetamides in alcohol solution of sodium ethoxide, forming various pyridin-2-ones. The cyclization direction of Michael adducts was affected by the nucleophilicity of cyanoacetamide used as a СН acid.

How to Cite
Fefelova, S. R.; Krasnikov, D. A.; Dyachenko, V. D.; Dyachenko, A. D. Chem. Heterocycl. Compd. 2014, 50, 1133. [Khim. Geterotsikl. Soedin. 2014, 1228.]

For this article in the English edition see DOI 10.1007/s10593-014-1573-5


Keywords


ethyl(1-phenylethylidene)cyanoacetate; cyanoacetamide; glutarimides; pyridin-2-ones; Michael addition

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