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CASCADE TWO- AND THREE-COMPONENT CYCLIZATION REACTIONS USING 1,2-DIAMINO-4-PHENYLIMIDAZOLE AND CYCLOHEXANE-1,3-DIONES

Д. Ю. Вандышев, Х. С. Шихалиев, А. Ю. Потапов, М. Ю. Крысин
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Abstract


The reaction of 1,2-diamino-4-phenylimidazole with 5,5-R,R1-cyclohexane-1,3-diones and with the dimethyl formamide dimethyl acetal or triethyl orthoformate gives 7,7-R,R1-3-amino-1-phenyl-7,8-di-hydroimidazo[1,5-b]cinnolin-9(6H)-ones in good yield. These products may also be obtained from 1,2‑diamino-4-phenylimidazole and 5,5-R,R1-(phenylaminomethylidene)cyclohexane-1,3-diones.

How to Cite
Vandyshev, D. Yu.; Shikhaliev, Kh. S.; Potapov, A. Yu.; Krysin, M. Yu. Chem. Heterocycl. Compd. 2014, 50, 1306. [Khim. Geterotsikl. Soedin. 2014, 1428.]

For this article in the English edition see DOI 10.1007/s10593-014-1594-0


Keywords


3-amino-7,8-dihydro-1-phenylimidazo[1,5-b]cinnolin-9(6H)-ones; cyclohexane-1,3-diones; 1,2-diamino-4-phenylimidazole; dimethyl formamide dimethyl acetal; 2-(phenylaminomethylidene)cyclohexane-1,3-diones; triethyl orthoformate; three-component condensation

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