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SYNTHESIS OF SUBSTITUTED 2-PYRIDONES USING ARYLAMIDOESTERS OF MALONIC ACID

С. С. Айоцян, А. Г. Асратян, С. Г. Конькова, А. Х. Хачатрян, А. Э. Бадасян, А. Г. Айвазян, Г. А. Паносян, М. С. Саргсян
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Abstract


With the aim of developing of the new methods for the synthesis of substituted 2-pyridones, the reaction of arylamidoesters of malonic acid with ethoxymethylideneacetylacetone in the presence of triethylamine in ethanol solution was studied. NMR spectroscopy and X-ray diffraction structural analysis of the reaction product indicated that the forming enedione undergoes the Michael reaction to provide substituted 2‑pyridones.

How to Cite
Hayotsyan, S. S.; Hasratyan, A. H.; Kon'kova, S. G.; Khachatryan, A. Kh.; Badasyan, A. E.; Ayvazyan, A. G.; Panosyan, G. A.; Sargsyan, M. S. Chem. Heterocycl. Compd. 2014, 50, 1126. [Khim. Geterotsikl. Soedin. 2014, 1221.]

For this article in the English edition see DOI 10.1007/s10593-014-1572-6


Keywords


amidoester of malonic acid; ethoxymethylideneacetylacetone; 2-pyridone; Michael addition

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