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SYNTHESIS OF 2-SUBSTITUTED (2R,4R)-3-(3-MERCAPTOPROPIONYL)THIAZOLIDINE-4-CARBOXYLIC ACIDS

A. Ю. Ершов, Д. Г. Наследов, И. В. Лагода, В. В. Шаманин
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Abstract


The natural amino acid L-cysteine, commercially available aldehydes, and 3-(acetylsulfanyl)propionyl chloride were used for the synthesis of 2-substituted (2R,4R)-3-(3-mercaptopropionyl)thiazolidine-4‑carboxylic acids, potential antihypertensive drugs with angiotensin converting enzyme inhibiting action.

How to Cite
Ershov, A. Yu.; Nasledov, D. G.; Lagoda, I. V.; Shamanin, V. V. Chem. Heterocycl. Compd. 2014, 50, 1032. [Khim. Geterotsikl. Soedin. 2014, 1119.]

For this article in the English edition see DOI 10.1007/s10593-014-1560-x


Keywords


aldehydes; 2-substituted 3-(3-mercaptopropionyl)thiazolidine-4 carboxylic acids; L-cysteine; angiotensin converting enzyme inhibitors

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