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SYNTHESIS OF NOVEL 4,4-DIALKYL- AND 4,4-DIARYLINDENO[1,2-b]THIOPHENES AND THEIR 2-BROMO DERIVATIVES

J. Bucevicius, P. Adomenas, S. Tumkevicius
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Abstract


A series of new 4,4-dialkyl- and 4,4-diaryl-4H-indeno[1,2-b]thiophenes and their 2-bromo derivatives were synthesized and characterized. An economical one-pot method for the preparation of the key starting material – 2-(2-thienyl)benzoic acid and improved procedures for the synthesis of indeno[1,2-b]thiophen-4-one and 4,4-dialkyl-4H-indeno[1,2-b]thiophenes have been developed. The described methods were shown to be efficient for the preparation of the title compounds on a multigram scale.

How to Cite
Bucevicius, J.; Adomenasp, P.; Tumkevicius, S. Chem. Heterocycl. Compd. 2015, 50, 1413. [Khim. Geterotsikl. Soedin. 2014, 1537.]

For this article in the English edition see DOI 10.1007/s10593-014-1605-1


Keywords


indeno[1,2-b]thiophenes; sulfur heterocycles; alkylation; bromination; Kumada coupling

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