SYNTHESIS, STRUCTURE, AND ANTIRADICAL ACTIVITY OF NEW METHANO[1,3]THIAZOLO[2,3-<i>d</i>][1,3,5]BENZOXADIAZOCINE DERIVATIVES

Authors

  • И. В. Кулаков Omsk F. M. Dostoevskii State University
  • С. А. Талипов Institute of Bioorganic Chemistry
  • З. Т. Шульгау Center for Life Sciences, Inc.
  • Т. М. Сейлханов Sh. Ualikhanov Kokshetau State University

DOI:

https://doi.org/10.1007/1920

Keywords:

2H-2, 6-methano[1, 3, 5]benzoxadiazocines, salicylic aldehyde, thiourea, Biginelli reaction, intramolecular heterocyclization, X-ray structural analysis

Abstract

The reaction of 2,6-methano[1,3,5]benzoxadiazocines, obtained in Biginelli reaction, with chloroacetic acid derivatives produced previously unknown tricyclic methano[1,3]thiazolo[2,3-d][1,3,5]benzoxadiazocines, the structure of which was proved by 1Н NMR spectroscopy and X-ray structural analysis. The methano[1,3]thiazolo[2,3-d][1,3,5]benzoxadiazocines showed no antiradical activity in contrast to the starting 2,6‑methano[1,3,5]benzoxadiazocines.

How to Cite
Kulakov, I. V.; Talipov, S. A.; Shulgau, Z. T.; Seilkhanov, T. M. Chem. Heterocycl. Compd. 2015, 50, 1478. [Khim. Geterotsikl. Soedin. 2014, 1604.]

For this article in the English edition see DOI 10.1007/s10593-014-1613-1

Author Biography

И. В. Кулаков, Omsk F. M. Dostoevskii State University

Иван Вячеславович Кулаков

д.х.н., профессор кафедры органической химии

Downloads

Published

2014-11-03

Issue

No. 10 (2014)

Section

Original Papers