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SYNTHESIS, STRUCTURE, AND ANTIRADICAL ACTIVITY OF NEW METHANO[1,3]THIAZOLO[2,3-d][1,3,5]BENZOXADIAZOCINE DERIVATIVES

И. В. Кулаков, С. А. Талипов, З. Т. Шульгау, Т. М. Сейлханов
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Abstract


The reaction of 2,6-methano[1,3,5]benzoxadiazocines, obtained in Biginelli reaction, with chloroacetic acid derivatives produced previously unknown tricyclic methano[1,3]thiazolo[2,3-d][1,3,5]benzoxadiazocines, the structure of which was proved by 1Н NMR spectroscopy and X-ray structural analysis. The methano[1,3]thiazolo[2,3-d][1,3,5]benzoxadiazocines showed no antiradical activity in contrast to the starting 2,6‑methano[1,3,5]benzoxadiazocines.

How to Cite
Kulakov, I. V.; Talipov, S. A.; Shulgau, Z. T.; Seilkhanov, T. M. Chem. Heterocycl. Compd. 2015, 50, 1478. [Khim. Geterotsikl. Soedin. 2014, 1604.]

For this article in the English edition see DOI 10.1007/s10593-014-1613-1


Keywords


2H-2,6-methano[1,3,5]benzoxadiazocines; salicylic aldehyde; thiourea; Biginelli reaction; intramolecular heterocyclization; X-ray structural analysis

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