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SYNTHESIS OF 1,4- AND 1,5-DIARYL-1H-IMIDAZOLES

V. S. Mityanov, V. P. Perevalov, I. I. Tkach
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Abstract


A simple method for the synthesis of 1,4- and 1,5-diarylimidazoles has been developed. The method is based on the condensation of appropriate α-diketone monooxime with aromatic amines and formaldehyde in the presence of boron trifluoride etherate leading to the formation of stable boron trifluoride complexes of imidazole N-oxides. Further reduction of these complexes led to the formation of corresponding imidazoles.

How to Cite
Mityanov, V. S.; Perevalov, V. P.; Tkach, I. I. Chem. Heterocycl. Compd. 2015, 50, 1534. [Khim. Geterotsikl. Soedin. 2014, 1669.]

For this article in the English edition see DOI 10.1007/s10593-014-1621-1


Keywords


boron trifluoride; 1,4-diarylimidazoles; 5-diarylimidazoles; imidazole N-oxides; cyclocondensation

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