2-ALKYL-4-OXOHEXAHYDROPYRIMIDO[4,5-d]- AND -[5,4-d]AZOCINES

Abstract

It has been established that 2-R-4-oxotetrahydropyrido[4,3-d]pyrimidines, under the action of activated alkynes in methanol, form a mixture of 2-R-4-oxohexahydropyrimido[4,5-d]azocines and products of decomposition of the tetrahydropyridine ring, the 2-R-5-methoxymethyl-4-oxo-6-vinylaminoethylpyrimidines. Tetrahydropyrido[3,4-d]pyrimidine, isomeric at the junction of the pyrimidine and tetrahydropyridine rings, forms only the corresponding pyrimido[5,4-d]azocine, the product of expansion, under the action of methyl propiolate.

How to Cite
Voskressensky, L. G.; Ovcharov, M. V.; Borisova, T. N.; Kulikova, L. N.; Listratova, A. V.; Borisov, R. S.; Varlamov, A. V. Chem. Heterocycl. Compd. 2011, 47(2), 222. [Khim. Geterotsikl. Soedin. 2011, 279.]

For this article in the English edition see DOI 10.1007/s10593-011-0744-x