NOVEL NUCLEOPHILIC REARRANGEMENT OF 1-SUBSTITUTED ISOQUINOLINES USING AN ALCOHOLIC SODIUM HYDROXIDE SOLUTION

Authors

  • В. И. Теренин M. V. Lomonosov State University
  • А. А. Волков M. V. Lomonosov State University
  • А. С. Иванов M. V. Lomonosov State University
  • Е. В. Кабанова M. V. Lomonosov State University

DOI:

https://doi.org/10.1007/2178

Keywords:

isoquinoline, isochroman-3-one, sodium ethylate, reduction, nucleophilic rearrangement

Abstract

The reactions of 1-substituted isoquinolinium salts have been studied in the cases of the 1-isopropyl-2‑methyl- and 2-methyl-1-cyclohexylisoquinolinium iodides using an alcoholic solution of sodium hydroxide. The possibility of preparing a wide range of spirocyclic ketones, alcohols, amino alcohols, and isochroman-3-ones has been demonstrated.

How to Cite
Terenin, V. I.; Volkov, A. A.; Ivanov, A. S.; Kabanova, E. V. Chem. Heterocycl. Compd. 2011, 47(1), 74. [Khim. Geterotsikl. Soedin. 2011, 98.]

For this article in the English edition see DOI 10.1007/s10593-011-0722-3

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Published

2014-12-18

Issue

No. 1 (2011)

Section

Original Papers