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SYNTHESIS OF 2-ARYL-4,5-BIS(POLYFLUOROALKYL)IMIDAZOLES FROM POLYFLUOROALKANETHIOCARBOXYLIC ACID AMIDES

Сергей С. Михайличенко, Надежда В. Пикун, Эдуард Б. Русанов, Юрий Г. Шермолович
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Abstract


Polyfluoroalkanethiocarboxylic acid amides react with aromatic aldehydes with the formation of bis(N-thioacyl)aminals. Treating the latter with acyl chlorides gives 2-aryl-substituted 4,5-bis(polyfluoroalkyl)imidazoles which constitutes a novel method of synthesizing these imidazole derivatives.

How to Cite
Mikhaylychenko, S. S.; Pikun, N. V.; Rusanov, E. B.; Shermolovich, Y. G. Chem. Heterocycl. Compd. 2015, 51, 128. [Khim. Geterotsikl. Soedin. 2015, 51, 128.]

For this article in the English edition see DOI 10.1007/s10593-015-1669-6


Keywords


aromatic aldehydes, 4,5-bis(polyfluoroalkyl)imidazoles; bis(N-thioacyl)aminals; polyfluoroalkanethiocarboxylic acid amides; acylation

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