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BASE-CATALYZED ADDITION OF KETONES TO ALKYNES AS A SPRINGBOARD TO CYCLOALKA[c]PYRAZOLINE-2-CARBALDEHYDES

Elena Yu. Schmidt, Elena V. Ivanova, Inna V. Tatarinova, Igor A. Ushakov, Nadezhda I. Protsuk, Boris A. Trofimov
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Abstract


Unknown cycloalka[c]pyrazoline-2-carbaldehydes are obtained in 52–68% yields when the intermediates of base-catalyzed addition of cyclic ketones to phenylacetylene are treated (without isolation) with hydrazine hydrate in formic acid.

How to Cite
Schmidt, E. Yu.; Ivanova, E. V.; Tatarinova, I. V.; Ushakov, I. A.; Protsuk, N. I.; Trofimov, B. A. Chem. Heterocycl. Compd. 2015, 51, 242. [Khim. Geterotsikl. Soedin. 2015, 51, 242.]

For this article in the English edition see DOI 10.1007/s10593-015-1691-8


Keywords


alkynes; carbaldehydes; ketones; pyrazolines; nucleophilic addition

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