A SIMPLE AND EFFICIENT SYNTHESIS OF SUBSTITUTED PYRAZOLES

Authors

  • Doddamani Shridevi Doddaramappa University of Mysore, Karnataka State, INDIA
  • - Chandra University of Mysore
  • M. Mahendra University of Mysore
  • K. M. Lokanatha Rai University of Mysore

DOI:

https://doi.org/10.1007/228

Keywords:

1, 3-diphenyl-1H-pyrazole, potassium hydroxide, pyrazole-5-carbonitrile, phase transfer catalyst, tetrabutylammonium bromide, X-ray study

Abstract

A novel route for the formation of 3-aryl-1-phenyl-1H-pyrazoles was discovered upon the reaction of 3-aryl-1-phenyl-4,5-dihydro-1H-pyrazole-5-carbonitrile with potassium hydroxide in the presence of phase transfer catalyst (tetrabutylammonium bromide) in THF as a solvent and a single crystal X-ray study is reported.

Also published in Chemistry of Heterocyclic Compounds, 2013, 49 (5), pp 698-703

http://link.springer.com/article/10.1007/s10593-013-1300-7

 

 


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Published

2013-05-07

Issue

No. 5 (2013)

Section

Original Papers