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A novel method for the synthesis of imidazo[1,5-b]pyridazines

Дмитрий Ю. Вандышев, Хидмет С. Шихалиев, Андрей Ю. Потапов, Михаил Ю. Крысин
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Abstract


Condensation of 4-phenylimidazole-1,2-diamine with 1-aryl-3-(dimethylamino)-2-propen-1-ones leads to the formation of 4-aryl-5phenylimidazo[1,5-b]pyridazin-7-amines, which smoothly react at the exocyclic amino group with acetic anhydride, phenyl isocyanate, and para-tolualdehyde.

How to Cite
Vandyshev, D. Yu.; Shikhaliyev, Kh. S.; Potapov, A. Yu.; Krysin, M. Yu. Chem. Heterocycl. Compd. 2015, 51, 573. [Khim. Geterotsikl. Soedin. 2015, 51, 573.]

For this article in the English edition see DOI 10.1007/s10593-015-1738-x

 


Keywords


1-aryl-3-(dimethylamino)prop-2-en-1-one; 4-aryl-5-phenylimidazo[1,5-b]pyridazin-7-amine; enaminone; 4-phenylimidazole-1,2-diamine; heterocyclization

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