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SYNTHESIS OF NEW BIS-SPIROOXINDOLOPYRROLIZIDINE(PYRROLIDINE) DERIVATIVES VIA A PSEUDO FIVE-COMPONENT 1,3-DIPOLAR CYCLOADDITION REACTION

Mohammad Javad Taghizadeh, Abdollah Javidan, Sajjad Keshipour
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Abstract


A comparative study of the synthesis of new bis-spirooxindolopyrrolizidine(pyrrolidine) ring systems by the cycloaddition of azomethine ylides with a bischalcone is performed. The azomethine ylide was generated in two steps including the condensation of sarcosine or proline with isatin and decarboxylation of the produced intermediate.

How to Cite
Taghizadeh, M. J.; Javidan, A.; Keshipour, S. Chem. Heterocycl. Compd. 2015, 51, 467. [Khim. Geterotsikl. Soedin. 2015, 51, 467.]

For this article in the English edition see DOI 10.1007/s10593-015-1722-5


Keywords


azomethine ylides; bisdipolarophiles; bis-spirooxindolopyrrolidines; bis-spirooxindolopyrrolizidines

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