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Single-stage synthesis of 3-hydroxy- and 3-alkoxy- 5-arylimidazolidine-2,4-diones by reaction of arylglyoxal hydrates with N-hydroxy- and N-alkoxyureas

Василий Г. Штамбург, Виктор В. Штамбург, Андрей А. Анищенко, Роман И. Зубатюк, Александр В. Мазепа, Евгений А. Клоц, Светлана В. Кравченко, Ремир Г. Костяновский
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Abstract


Arylglyoxal hydrates interact with N-alkoxyureas and N-hydroxyurea in acetic acid with selective formation of 3-alkoxy-5-arylimidazolidine-2,4-diones and 5-aryl-3-hydroxyimidazolidine-2,4-diones, respectively. The structures of 3-methoxy-5-phenylimidazolidine-2,4-dione, 3-ethoxy-5-phenylimidazolidine-2,4-dione, and 3-butoxy-5-(4-chlorophenyl)imidazolidine-2,4-dione were studied by X-ray structural analysis.

How to Cite
Shtamburg, V. G.; Shtamburg, V. V.; Anishchenko, A. A.; Zubatyuk, R. I.; Mazepa, A. V.; Klotz, E. A.; Kravchenko, S. V.; Kostyanovsky, R. G. Chem. Heterocycl. Compd. 2015, 51, 553. [Khim. Geterotsikl. Soedin. 2015, 51, 553.]

For this article in the English edition see DOI 10.1007/s10593-015-1735-0

 


Keywords


3-alkoxy-5-arylimidazolidine-2,4-diones; N-alkoxyureas; arylglyoxals; 5-aryl-3-hydroxyimidazolidine-2,4-diones; N-hydroxyurea; cyclization; X-ray structural analysis

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