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A SIMPLE METHOD FOR THE SYNTHESIS OF FURFURYL KETONES AND FURYLACETIC ACID DERIVATIVES

Петракис Н. Чаликиди, Татьяна А. Неволина, Максим Г. Учускин, Владимир Т. Абаев, Александр В. Бутин
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Abstract


A simple preparative method has been developed for the synthesis of aryl(furfuryl) ketones, amides, and furylacetic acid esters, based on radical alkylation of furan derivatives at the α-position with О-ethyl(phenacyl)xanthogenates and phenacyl iodides in the presence of Fenton's reagent (H2O2/FeSO4∙7H2O) in DMSO. The range of applicability and mechanisms for the formation of major and side products have been considered.

How to Cite
Chalikidi, P. N.; Nevolina, T. A.; Uchuskin, M. G.; Abaev, V. T.; Butin, A. V. Chem. Heterocycl. Compd. 2015, 51, 621. [Khim. Geterotsikl. Soedin. 2015, 51, 621.]

For this article in the English edition see DOI 10.1007/s10593-015-1744-z

 


Keywords


furans; furylacetamides; furfuryl ketones; esters of furylacetic acids; radical alkylation

Full Text: PDF (Russian) Supplementary File(s): Supporting information (4MB)


 

 

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