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PRODUCTS FROM THE ADDITION OF ACETOACETIC ESTER OR ACETYLACETONE TO 3-NITRO-2Н-CHROMENES – AXIALLY CHIRAL trans,trans-2,3,4-TRISUBSTITUTED CHROMANS AND RELATED PYRAZOLES

Владислав Ю. Коротаев, Игорь Б. Кутяшев, Алексей Ю. Барков, Марина А. Ежикова, Михаил И. Кодесс, Вячеслав Я. Сосновских
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Abstract


The trans,trans-2,3,4-trisubstituted chromans, previously described by us as addition products of acetoacetic ester or acetylacetone at the activated double bond of 2-substituted 3-nitro-2Н-chromenes, are axially chiral molecules due to the hindered rotation around the C(sp3)–C(sp2) bond.

How to Cite
Korotaev, V. Yu.; Kutyashev, I. B.; Barkov, A. Yu.; Ezhikova, M. A.; Kodess, M. I.; Sosnovskikh, V. Ya. Chem. Heterocycl. Compd. 2015, 51, 704. [Khim. Geterotsikl. Soedin. 2015, 51, 704.]

For this article in the English edition see DOI 10.1007/s10593-015-1762-x


Keywords


chromans; 1,3-dicarbonyl compounds; 3-nitro-2Н-chromenes; pyrazoles; atropisomerism; nucleophilic addition

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