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SYNTHESIS OF DIMETHYL ESTERS OF 7-OXO-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-c]PYRIMIDINE-2,3-DICARBOXYLIC ACID

Римма М. Султанова, Александр Н. Лобов, Леонид В. Спирихин
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Abstract


3-Diazopyrrolidones, prepared by nitrosation of 3-aminopyrrolidones with isoamyl nitrite in the presence of glacial acetic acid, enter in a 1,3-dipolar cycloaddition reaction with dimethyl ester of acetylenedicarboxylic acid to form tetrahydropyrazolo[1,5-c]pyrimidines in good yields.

How to Cite
Sultanova, R. M.; Lobov, A. N.; Spirikhin, L. V. Chem. Heterocycl. Compd. 2015, 51, 1048. [Khim. Geterotsikl. Soedin. 2015, 51, 1048.]

For this article in the English edition see DOI 10.1007/s10593-016-1817-7


Keywords


alkynes; diazopyrrolidones; pyrazoles; tetrahydropyrazolo[1,5-c]pyrimidines; 1,3-dipolar cycloaddition; [1,5]-sigmatropic rearrangement

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