A NOVEL SYNTHESIS OF (<i>E</i>)-1-(2-HYDROXYPHENYL)-3-(1<i>Н</i>-INDOL-3-YL)-PROP-2-EN-1-ONES FROM CHROMONE-3-CARBOXYLIC ACID AND INDOLES

Authors

  • Михаил Ю. Корнев Institute of Natural Sciences of Ural Federal University, 51 Lenin Ave., Yekaterinburg 620000
  • Владимир С. Мошкин Institute of Natural Sciences of Ural Federal University, 51 Lenin Ave., Yekaterinburg 620000
  • Вячеслав Я. Сосновских Institute of Natural Sciences of Ural Federal University, 51 Lenin Ave., Yekaterinburg 620000

DOI:

https://doi.org/10.1007/2659

Keywords:

chromone-3-carboxylic acid, indolyl chalcones, indoles, Michael addition

Abstract

The reaction of chromone-3-carboxylic acid with indoles in boiling ethanol proceeds as a 1,4-nucleophilic addition with successive opening of the pyrone ring and decarboxylation to afford a series of previously unknown trans-indolyl chalcones in 27–60% yields.

How to Cite
Kornev, M. Yu.; Moshkin, V. S.; Sosnovskikh, V. Ya. Chem. Heterocycl. Compd. 2015, 51, 858. [Khim. Geterotsikl. Soedin. 2015, 51, 858.]

For this article in the English edition see DOI 10.1007/s10593-015-1786-2

Author Biography

Вячеслав Я. Сосновских, Institute of Natural Sciences of Ural Federal University, 51 Lenin Ave., Yekaterinburg 620000

Зав. кафедрой органической химии Института естественных наук Уральского федерального университета

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Published

2015-10-23

Issue

Vol. 51 No. 9 (2015)

Section

Letters to the Editor