REVERSIBLE CONDENSATION OF 4-ARYLIDENE-1,2-DIMETHYL-1<i>H</i>-IMIDAZOL-5(4<i>H</i>)-ONES WITH AROMATIC ACYL CHLORIDES

Authors

  • Светлана В. Голодухина Institute of Bioorganic Chemistry named after Academicians M. M. Shemyakin and Yu. A. Ovchinnikov, Russian Academy of Sciences
  • Надежда С. Балеева Institute of Bioorganic Chemistry named after Academicians M. M. Shemyakin and Yu. A. Ovchinnikov, Russian Academy of Sciences; Russian National Research Medical University named after N. I. Pirogov
  • Константин С. Минеев Institute of Bioorganic Chemistry named after Academicians M. M. Shemyakin and Yu. A. Ovchinnikov, Russian Academy of Sciences
  • Михаил С. Баранов Institute of Bioorganic Chemistry named after Academicians M. M. Shemyakin and Yu. A. Ovchinnikov, Russian Academy of Sciences; Russian National Research Medical University named after N. I. Pirogov

DOI:

https://doi.org/10.1007/2660

Keywords:

imidazolones, chromophores, fluorescent proteins, condensation

Abstract

(Z)-1,2-Dimethyl-4-(4-methoxybenzylidene)-1H-imidazol-5(4H)-one underwent a condensation reaction with aromatic acyl chlorides, forming keto derivatives that were structurally similar to chromophores of red fluorescent proteins, as well as to the products of their maturation and/or degradation. The reverse reaction of the obtained products was observed upon treatment with aqueous alkali.

How to Cite
Golodukhina, S. V.; Baleev, N. S.; Mineyev, K. S.; Baranov, M. S. Chem. Heterocycl. Compd. 2015, 51, 944. [Khim. Geterotsikl. Soedin. 2015, 51, 944.]

For this article in the English edition see DOI 10.1007/s10593-015-1802-6

Author Biographies

Светлана В. Голодухина, Institute of Bioorganic Chemistry named after Academicians M. M. Shemyakin and Yu. A. Ovchinnikov, Russian Academy of Sciences

Светлана Владимировна Голодухина

Надежда С. Балеева, Institute of Bioorganic Chemistry named after Academicians M. M. Shemyakin and Yu. A. Ovchinnikov, Russian Academy of Sciences; Russian National Research Medical University named after N. I. Pirogov

Надежда Сергеевна Балеева

Константин С. Минеев, Institute of Bioorganic Chemistry named after Academicians M. M. Shemyakin and Yu. A. Ovchinnikov, Russian Academy of Sciences

Константин Сергеевич Минеев

Михаил С. Баранов, Institute of Bioorganic Chemistry named after Academicians M. M. Shemyakin and Yu. A. Ovchinnikov, Russian Academy of Sciences; Russian National Research Medical University named after N. I. Pirogov

Михаил Сергеевич Баранов

К. х. н., н. с.

С 2009 года сотрудник лаборатории биофотоники ИБХ РАН.

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Published

2015-10-29

Issue

Vol. 51 No. 10 (2015)

Section

Letters to the Editor