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BiCl3 – AN ECO-FRIENDLY CATALYST FOR AN EFFICIENT SYNTHESIS OF BENZOXAZOLES AT ROOM TEMPERATURE

Vishvanath D. Patil, Nagesh R. Sutar, Ketan P. Patil, Prathamesh V. Giddh
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Abstract


A simple and efficient protocol has been developed for the synthesis of 2-arylbenzoxazole derivatives of potential pharmaceutical interest. The method involves reaction between 2-aminophenol and substituted aromatic aldehydes in the presence of anhydrous bismuth trichloride as catalyst in acetonitrile. The use of eco-friendly bismuth trichloride, overall mild reaction conditions, and moderate to good yield of products are some attractive features of this methodology.

How to Cite
Patil, V. D.; Sutar, N. R.; Patil, K. P.; Giddh, P. Chem. Heterocycl. Compd. 2015, 51, 1019. [Khim. Geterotsikl. Soedin. 2015, 51, 1019.]

For this article in the English edition see DOI 10.1007/s10593-016-1814-x


Keywords


benzoxazole; bismuth trichloride; eco-friendly catalyst

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