Open Access Open Access  Restricted Access Subscription Access

[C8dabco]Br: A MILD AND CONVENIENT CATALYST FOR INTRAMOLECULAR CYCLIZATION OF 2-AMINOCHALCONES TO THE CORRESPONDING 2-ARYL-2,3-DIHYDROQUINOLIN-4(1H)-ONES

Chamseddine Derabli, Sara Mahdjoub, Raouf Boulcina, Boudjemaa Boumoud, Hocine Merazig, Abdelmadjid Debache
Cover Image

Abstract


A new and convenient synthesis of 2-aryl-2,3-dihydroquinolin-4(1H)-ones has been described using the intramolecular cyclization of 2-aminochalcones catalyzed by 1-octyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide ([C8dabco]Br). Recyclability of the catalyst, high yields, simple isolation of the products, and high atom economy are the noteworthy aspects of the protocol.

How to Cite
Derabli, C.; Mahdjoub, S.; Boulcina, R.; Boumoud, B.; Merazig, H.; Debache, A. Chem. Heterocycl. Compd. 2016, 52, 99. [Khim. Geterotsikl. Soedin. 2016, 52, 99.]

For this article in the English edition see DOI 10.1007/s10593-016-1840-8


Keywords


2-aryl-2,3-dihydroquinolin-4(1H)-ones; [C8dabco]Br; ionic liquids; aza-Michael reaction; cyclization

Full Text: PDF Supplementary File(s): SUPPLEMENTARY INFORMATION (2MB)


 

 

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv