[C<sub>8</sub>dabco]Br: A MILD AND CONVENIENT CATALYST FOR INTRAMOLECULAR CYCLIZATION OF 2-AMINOCHALCONES TO THE CORRESPONDING 2-ARYL-2,3-DIHYDROQUINOLIN-4(1<i>H</i>)-ONES

Authors

  • Chamseddine Derabli Laboratory of Synthesis of Molecules with Biological Interest, University of Constantine 1
  • Sara Mahdjoub Laboratory of Synthesis of Molecules with Biological Interest, University of Constantine 1
  • Raouf Boulcina Laboratory of Synthesis of Molecules with Biological Interest, University of Constantine 1
  • Boudjemaa Boumoud Laboratory of Synthesis of Molecules with Biological Interest, University of Constantine 1
  • Hocine Merazig Chemistry Research Unit in Environmental and Molecular Structure, University of Constantine 1
  • Abdelmadjid Debache Laboratory of Synthesis of Molecules with Biological Interest, University of Constantine 1

DOI:

https://doi.org/10.1007/2671

Keywords:

2-aryl-2, 3-dihydroquinolin-4(1H)-ones, [C8dabco]Br, ionic liquids, aza-Michael reaction, cyclization

Abstract

A new and convenient synthesis of 2-aryl-2,3-dihydroquinolin-4(1H)-ones has been described using the intramolecular cyclization of 2-aminochalcones catalyzed by 1-octyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide ([C8dabco]Br). Recyclability of the catalyst, high yields, simple isolation of the products, and high atom economy are the noteworthy aspects of the protocol.

How to Cite
Derabli, C.; Mahdjoub, S.; Boulcina, R.; Boumoud, B.; Merazig, H.; Debache, A. Chem. Heterocycl. Compd. 2016, 52, 99. [Khim. Geterotsikl. Soedin. 2016, 52, 99.]

For this article in the English edition see DOI 10.1007/s10593-016-1840-8

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Published

2016-03-13

Issue

Vol. 52 No. 2 (2016)

Section

Original Papers