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ALKYLIDENE AND ARYLIDENE MELDRUM'S ACIDS AS VERSATILE REAGENTS FOR THE SYNTHESIS OF HETEROCYCLES

Inese Mieriņa, Māra Jure
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Abstract


Meldrum's acid and its derivatives are excellent building blocks for the synthesis of acyclic, carbocyclic and heterocyclic compounds. Herein recent (mainly 2010–2015) trends on applications of arylidene/alkylidene Meldrum's acids (R1, R2 = H, Ar, Alk, –(CH2)n–) in the synthesis of heterocycles and multicomponent reactions (MCR) involving in situ formation of arylidene/alkylidene Meldrum's acids are focused.

How to Cite
Mieriņa, I.; Jure, M. Chem. Heterocycl. Compd. 2016, 52, 7. [Khim. Geterotsikl. Soedin. 2016, 52, 7.]

For this article in the English edition see DOI 10.1007/s10593-016-1822-x

 


Keywords


arylidene Meldrum's acid; alkylidene Meldrum's acid; 5-arylidene-2,2-dimethyl-1,3-dioxan-4,6-dione; 5-alkylidene-2,2-dimethyl-1,3-dioxan-4,6-dione; multicomponent reaction

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