

ALKYLIDENE AND ARYLIDENE MELDRUM'S ACIDS AS VERSATILE REAGENTS FOR THE SYNTHESIS OF HETEROCYCLES

Abstract
Meldrum's acid and its derivatives are excellent building blocks for the synthesis of acyclic, carbocyclic and heterocyclic compounds. Herein recent (mainly 2010–2015) trends on applications of arylidene/alkylidene Meldrum's acids (R1, R2 = H, Ar, Alk, –(CH2)n–) in the synthesis of heterocycles and multicomponent reactions (MCR) involving in situ formation of arylidene/alkylidene Meldrum's acids are focused.
How to Cite
Mieriņa, I.; Jure, M. Chem. Heterocycl. Compd. 2016, 52, 7. [Khim. Geterotsikl. Soedin. 2016, 52, 7.]
For this article in the English edition see DOI 10.1007/s10593-016-1822-x
Keywords
arylidene Meldrum's acid; alkylidene Meldrum's acid; 5-arylidene-2,2-dimethyl-1,3-dioxan-4,6-dione; 5-alkylidene-2,2-dimethyl-1,3-dioxan-4,6-dione; multicomponent reaction
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv