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NH-1,2,3-TRIAZOLES: SYNTHESIS AND REACTIONS WITH ELECTROPHILIC AGENTS

Василий A. Бакулев, Татьяна В. Березкина
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Abstract


A renewal of interest in the chemistry of 1,2,3-triazoles has occurred since the beginning of the 21st century. The application of metal catalysis and organocatalysis to the classical Huisgen1–5 and Dimroth reactions6,7 has provided access to a wide range of 1,2,3-triazole derivatives for a variety of chemical and biological studies. This, in turn, has resulted in the use of these compounds in biological and medicinal chemistry, technology, and medicine.8,9 In this report we focus on using the tandem process involving the formation of NH-1,2,3-triazoles and their reactions with electrophilic reactants in the synthesis of 1,4,5-substituted 1,2,3-triazoles.

How to Cite
Bakulev, V. A.; Beryozkina, T. A. Chem. Heterocycl. Compd. 2016, 52, 4. [Khim. Geterotsikl. Soedin. 2016, 52, 4.]

For this article in the English edition see DOI 10.1007/s10593-016-1821-y

 


Keywords


1,2,3-триазол; реакциям Хьюсгена; Димрота

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