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NOVEL 3-ACETYL-2-METHYL-POLYFLUOROCHROMONES IN REACTIONS WITH AMINES AND ESTERS OF AMINO ACIDS

Константин В. Щербаков, Денис Н. Бажин, Янина В. Бургарт, Виктор И. Салоутин
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Abstract


Novel 3-acetyl-2-methyl-polyfluoro-4Н-chromen-4-ones were obtained via one-pot acylation of acetylacetone with polyfluorobenzoyl chlorides. These chromones were shown to form N-substituted 3-amino-1-[2-hydroxy(polyfluoro)phenyl]but-2-en-1-ones in reaction with aliphatic primary amines, esters of amino acids, and aqueous ammonia via opening of the pyrone ring and deacylation.

How to Cite
Shcherbakov, K. V.; Bazhin, D. N.; Burgart, Ya. V.; Saloutin, V. I. Chem. Heterocycl. Compd. 2015, 51, 961. [Khim. Geterotsikl. Soedin. 2015, 51, 961.]

For this article in the English edition see DOI 10.1007/s10593-016-1805-y

 


Keywords


amine; chromone; acylation; deacylation; ring opening.

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