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MICROWAVE-ASSISTED ONE-POT SYNTHESIS OF PYRAZOLYL-SUBSTITUTED BENZOCHROMAN-4-ONE DERIVATIVES AND EVALUATION OF THEIR ANTICANCER ACTIVITY

Dongamanti Ashok, Kadiyala Padmavati, Bommidi Vijaya Lakshmi, Madderla Sarasija
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Abstract


Hybrid compounds containing both flavanone and pyrazole moieties have been synthesized from acetylnaphthols and pyrazole-4-carbaldehydes in good yields using microwave irradiation in a one-step procedure. The synthesized compounds were evaluated for their anticancer activity against four human cancer cell lines.

How to Cite
Ashok, D.; Padmavati, K.; Vijaya Lakshmi, B.; Sarasija, M. Chem. Heterocycl. Compd. 2016, 52, 15. [Khim. Geterotsikl. Soedin. 2016, 52, 15.]

For this article in the English edition see DOI 10.1007/s10593-016-1824-8


Keywords


1-(1-hydroxynaphthalen-2-yl)ethanone; 1-(2-hydroxynaphthalen-2-yl)ethanone; anticancer activity; microwave irradiation

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