SYNTHESIS OF 4-AMINO-SUBSTITUTED TETRAHYDROPYRIMIDO[4,5-<i>d</i>]AZOCINES

Authors

  • Л. Г. Воскресенский Peoples Friendship University of Russia
  • М. В. Овчаров Peoples' Friendship University of Russia
  • Т. Н. Борисова Peoples' Friendship University of Russia
  • А. В. Листратова Peoples' Friendship University of Russia
  • Л. Н. Куликова Peoples' Friendship University of Russia
  • Е. А. Сорокина Peoples' Friendship University of Russia
  • С. П. Громов Photochemistry Center, Russian Academy of Sciences
  • А. В. Варламов Peoples' Friendship University of Russia

DOI:

https://doi.org/10.1007/279

Keywords:

4-aminopyrimidoazocine, vinylpyrimidine, ring cleavage, ring enlargement, Hofmann cleavage, tandem transformation

Abstract

A method for the preparation of 4-amino-substituted tetrahydropyrimido[4,5-d]azocines containing an aromatic pyrimidine fragment has been developed. It was established that tetrahydropyrido[4,3-d]pyrimidines are cleaved by the action of activated alkynes with the formation of 6-vinylpyrimidines.

Authors: L. G. Voskressensky, M. V. Ovcharov, T. N. Borisova, A. V. Listratova, L. N. Kulikova, E. A. Sorokina, S. P. Gromov, and A. V. Varlamov.

English Translation in Chemistry of Heterocyclic Compounds, 2013, 49 (8), pp 1180-1187

http://link.springer.com/article/10.1007/s10593-013-1361-7

Author Biography

Л. Г. Воскресенский, Peoples Friendship University of Russia

Organic Chemistry Department, professor

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Published

2013-06-17

Issue

No. 8 (2013)

Section

Original Papers