POLYFUNCTIONAL PYRAZOLES. 6. CONVENIENT METHOD FOR THE SYNTHESIS OF 1-ARYL-1<i>H</i>-PYRAZOLE-3,4-DICARBOXYLIC ACIDS

Authors

  • М. К. Братенко Bukovinian State Medical University
  • М. М. Барус Bukovinian State Medical University
  • М. В. Вовк Institute of Organic Chemistry, National Academy of Sciences of Ukraine

DOI:

https://doi.org/10.1007/2803

Keywords:

pyrazole-3, 4-dicarboxylic acids, 4-formylpyrazole-3-carboxylic esters, aqueous medium, hydrolysis, oxidation

Abstract

A preparatively convenient method was developed for the synthesis of 1-aryl-1H-pyrazole-3,4-dicarboxylic acids based on the alkaline hydrolysis and oxidation of 1-aryl-4-formyl-1H-pyrazole-3‑carboxylic esters with hydrogen peroxide in an aqueous medium.

How to Cite
Bratenko, M. K.; Barus, M. M.; Vovk, M. V. Chem. Heterocycl. Compd. 2010, 46, 196. [Khim. Geterotsikl. Soedin. 2010, 243.]

For this article in the English edition see DOI 10.1007/s10593-010-0491-4

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Published

2015-11-26

Issue

No. 2 (2010)

Section

Original Papers