A CONVENIENT ROUTE FOR THE SYNTHESIS OF SOME NEW BI- AND TRIHETEROCONDENSED URACILS

Authors

  • M. Abdel-Megid Chemistry Department, Faculty of Education, Ain-Shams University

DOI:

https://doi.org/10.1007/2837

Keywords:

biheterocycles, triheterocycles, enaminones, uracil, antimicrobial activity

Abstract

Some bifunctional heterocyclic systems having vicinal chloro-cyano, chloro-acetyl, and chloro-ethoxycarbonyl groups in their structures reacted with 6-amino-1,3-dimethyluracil to afford novel triheterocyclic systems having a pyrimidinedione moiety. Enaminones and α-cyanocinnamic acid derivatives in this reaction gave pyrido[2,3-d]pyrimidinediones. The antimicrobial activity of some new synthesized triheterocyclic systems was studied.

How to Cite
Abdel-Megid, M. Chem. Heterocycl. Compd. 2010, 46, 316. [Khim. Geterotsikl. Soedin. 2010, 405.]

For this article in the English edition see DOI 10.1007/s10593-010-0507-0

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Published

2015-12-03

Issue

No. 3 (2010)

Section

Original Papers