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ISOXAZOLO[4,3-e]INDAZOLE AS A NEW HETEROCYCLIC SYSTEM: DESIGN, SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION, AND ANTIBACTERIAL ACTIVITY

Masoumeh Ghaemi, Mehdi Pordel
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Abstract


The new heterocyclic system isoxazolo[4,3-e]indazole was synthesized via the nucleophilic substitution of a hydrogen in 1-methyl-5-nitro-1H-indazole with different aryl acetonitriles in basic medium. The fluorescence properties and antibacterial activities of the new compounds against Gram-positive and Gram-negative bacterial species were also studied.

How to Cite
Ghaemi, M.; Pordel, M. Chem. Heterocycl. Compd. 2016, 52, 52. [Khim. Geterotsikl. Soedin. 2016, 52, 52.]

For this article in the English edition see DOI 10.1007/s10593-016-1833-7


Keywords


indazole; isoxazole; antibacterial activity; emission and absorption spectra; fluorescence

Full Text: PDF Supplementary File(s): Supporting information (2MB)


 

 

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