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RECENT TRENDS IN THE SYNTHESIS OF 1,3-OXAZINES

Aamer Saeed, Rabia Qamar
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Abstract


1,3-Oxazine is one of the privileged heterocyclic motifs exhibiting significant pharmacologicaland materials applications, besides, they are also used as intermediates in the synthesis of a broad range of heterocyclic compounds and polymers.The recent synthetic methodologies for the synthesis of 1,3-oxazines, fused and spiro-1,3-oxazines can be classified into several groups: multicomponent reactions, cyclization reactions, and temperature-dependent Rh(II)-carbenoid-mediated 2H-azirine ring expansion. In this microreview we have emphasized on these synthetic approaches for the synthesis of 1,3-oxazines.

How to Cite
Saeed, A.; Qamar, R. Chem. Heterocycl. Compd. 2016, 52, 96. [Khim. Geterotsikl. Soedin. 2016, 52, 96.]

For this article in the English edition see DOI 10.1007/s10593-016-1839-1

 


Keywords


1,3-oxazine; heterocyle; synthesis

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