SYNTHESIS AND CRYSTAL STRUCTURE OF SOME 3,5-PYRAZOLIDINEDIONES

Authors

  • Saoud A. M. Metwally Chemistry Department, Assiut University
  • Maisa I. Abdel Moneim Chemistry Department, Assiut University
  • Yasser A. Elossely Chemistry Department, Assiut University
  • Radwa I. Awad Forensic medicine laboratories
  • Khaled Abou-Hadeed Institute of Organic Chemistry, University of Zurich

DOI:

https://doi.org/10.1007/2945

Keywords:

3, 5-pyrazolidinediones, X-ray crystallography

Abstract

Syntheses of various derivatives of 3,5-pyrazolidenedione are reported. This includes 4-arylidene (alkylidene or aralkylidene)-3,5-pyrazolidinediones, which on epoxidation gave unreported oxiranes. The syntheses of these derivatives were based on either Knoevenagel reaction of carbonyl derivatives with 3,4-pyrazolidinedione or cyclization of arylidene (alkylidene)  malonic  acid  hydrazide with glacial acetic acid. 4-Arylazo-3,5-pyrazolidinedione derivatives were also prepared by coupling of aryldiazonium salts with 3,5-pyrazolidinedione or cyclization of arylazomalonic acid hydrazide. Reduction of 4-benzylidene derivatives gave the corresponding benzyl derivatives. The structure of the new products was confirmed by elemental and spectral analyses, and X-ray crystallography.

How to Cite
Metwally, S. A. M.; Moneim, M. I. A.; Elossely, Y. A.; Awad, R. I.; Abou-Hadeed, K. Chem. Heterocycl. Compd. 2010, 46, 426. [Khim. Geterotsikl. Soedin. 2010, 538.]

For this article in the English edition see DOI 10.1007/s10593-010-0527-9

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Published

2016-01-13

Issue

No. 4 (2010)

Section

Original Papers