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A FACILE APPROACH TO α,β-UNSATURATED LACTAMS BY RING-CLOSING METATHESIS

Humaira Yasmeen Gondal, Didier Buisson
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Abstract


A facile and efficient strategy for the synthesis of α,β-unsaturated lactams through ring-closing metathesis of easily prepared diene amides is being reported here. Reaction conditions were optimized for metathetic cyclization of diene amides to obtain five- to seven-membered unsubstituted and β-substituted α,β-unsaturated lactams in good to excellent yield.

How to Cite
Gondal, H. Y.; Buisson, D. Chem. Heterocycl. Compd. 2016, 52, 183. [Khim. Geterotsikl. Soedin. 2016, 52, 183.]

For this article in the English edition see DOI 10.1007/s10593-016-1858-y


Keywords


α,β-unsaturated lactams; Grubbs catalyst; ring-closing metathesis

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