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SYNTHESIS OF FURO[3,2-c]COUMARINS UNDER MICROWAVE IRRADIATION USING NANO-CoFe2O4@SiO2–PrNH2 AS AN EFFICIENT AND MAGNETICALLY REUSABLE CATALYST

Javad Safaei-Ghomi, Hossein Shahbazi-Alavi, Pouria Babaei, Hadi Basharnavaz, Stephen G. Pyne, Anthony C. Willis
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Abstract


CoFe2O4@SiO2–PrNH2 nanoparticles have been used as an efficient and magnetically recoverable catalyst for the preparation of trans-3-aryl-2-(4-bromobenzoyl)-2,3-dihydro-4H-furo[3,2-c]chromen-4-ones by multicomponent reaction of 2,4'-dibromoacetophenone, aromatic aldehydes, and 4-hydroxycoumarin in the presence of pyridine in ethanol under microwave irradiation. It was demonstrated by 1H NMR spectroscopy and single crystal analysis that the obtained furo[3,2-c]coumarins were the trans-isomers.

Keywords


CoFe2O4@SiO2–PrNH2; furo[3,2-c]coumarins; diastereoselectivity; one-pot synthesis; reusable catalysts

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