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SYNTHESIS OF PYRIDO[2,3-b][1,4]BENZOXAZEPINES VIA A FRIEDEL−CRAFTS CYCLIZATION

S. Guo, X. Zhong, B. Gong, H. Cui, J. Xiang
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Abstract


An efficient and practical method has been developed for the synthesis of 6-aryl-substituted pyrido[2,3-b][1,4]benzoxazepines via a Friedel−Crafts reaction of readily accessible 2-phenoxypyridin-3-amines and aromatic acids.


Keywords


2-phenoxypyridin-3-amine; pyrido[2,3-b][1,4]benzoxazepine; tricyclic compounds; Friedel−Crafts cyclization

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