NEW ROUTE FOR THE SYNTHESIS OF <i>N</i>-ALKYL-2-(PHENYLSULFONYL)ANILINES

Authors

  • Aisha Hossan Department of Chemistry, Faculty of Science of Girls, King Khalid University, Abha, Saudi Arabia

DOI:

https://doi.org/10.1007/3159

Keywords:

alkylammonium sulfites, diaryl sulfones, 2-[(phenylsulfonyl)methyl]pyridine, pyridinium salts, sodium benzenesulfinate

Abstract

The main objective of this work was to study the rearrangement reactions of 1-alkyl-2-[(phenylsulfonyl)methyl]pyridinium iodides in the presence of various nucleophiles, leading to N-alkyl-2-(phenylsulfonyl)aniline derivatives. The best results were achieved with alkylammonium sulfites, leading to pyridine ring opening followed by recyclization to give diphenyl sulfone derivatives in up to 78% yields.

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Published

2016-08-26

Issue

Vol. 52 No. 8 (2016)

Section

Original Papers