SOLVENT-FREE MICROWAVE-ASSISTED SYNTHESIS AND BIOLOGICAL EVALUATION OF AURONES AND FLAVANONES BASED ON 2,2-DIMETHYLCHROMAN-4-ONE

Authors

  • D. Ashok Green and Medicinal Chemistry Laboratory, Department of Chemistry, Osmania University, Hyderabad 500007
  • R. S. Kumar Richmond Vivek Laboratories, Mallapur, Hyderabad 500076
  • D. Mohan Gandhi Green and Medicinal Chemistry Laboratory, Department of Chemistry, Osmania University, Hyderabad 500007
  • A. Jayasree Center for Chemical Science and Technology, IST, JNTUH, Hyderabad 500085

DOI:

https://doi.org/10.1007/3161

Keywords:

aurones, chromanones, flavanones, antimicrobial activity, antioxidant activity

Abstract

A series of novel 8-aryl-2,2-dimethyl-2,3,7,8-tetrahydropyrano[3,2-g]chromene-4,6-dione and 2-arylidene-7,7-dimethyl-6,7-dihydro-2H-furo[3,2-g]chromene-3,5-dione derivatives have been synthesized by oxidation of the corresponding chalcones under microwave irradiation. All newly synthesized compounds were characterized by IR, 1H, 13C NMR, and mass spectra and valuated for their in vitro antibacterial and antifungal activities.

Downloads

Published

2016-06-17

Issue

Vol. 52 No. 7 (2016)

Section

Original Papers