Open Access Open Access  Restricted Access Subscription Access

SOLVENT-FREE MICROWAVE-ASSISTED SYNTHESIS AND BIOLOGICAL EVALUATION OF AURONES AND FLAVANONES BASED ON 2,2-DIMETHYLCHROMAN-4-ONE

D. Ashok, R. S. Kumar, D. Mohan Gandhi, A. Jayasree
Cover Image

Abstract


A series of novel 8-aryl-2,2-dimethyl-2,3,7,8-tetrahydropyrano[3,2-g]chromene-4,6-dione and 2-arylidene-7,7-dimethyl-6,7-dihydro-2H-furo[3,2-g]chromene-3,5-dione derivatives have been synthesized by oxidation of the corresponding chalcones under microwave irradiation. All newly synthesized compounds were characterized by IR, 1H, 13C NMR, and mass spectra and valuated for their in vitro antibacterial and antifungal activities.


Keywords


aurones; chromanones; flavanones; antimicrobial activity; antioxidant activity

Full Text: PDF Supplementary File(s): Supporting information (685KB)


 

 

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv