Fe<sub>3</sub>O<sub>4</sub> NANOPARTICLES AS AN EFFICIENT AND REUSABLE CATALYST FOR THE SOLVENT‐FREE SYNTHESIS OF 1<i>H</i>-INDOLE AND 1<i>H</i>-PYRROLE DERIVATIVES

Authors

  • S. E. Babaei Department of Chemistry, Qaemshahr Branch, Islamic Azad University, P.O. Box 163, Qaemshahr
  • Z. Hossaini Department of Chemistry, Qaemshahr Branch, Islamic Azad University, P.O. Box 163, Qaemshahr
  • R. Ramezani Besheli Department of Chemistry, Qaemshahr Branch, Islamic Azad University, P.O. Box 163, Qaemshahr
  • V. Tavakkoli Department of Chemistry, South of Tehran Branch, Islamic Azad University, P.O. Box 11, Tehran

DOI:

https://doi.org/10.1007/3163

Keywords:

activated acetylenic compounds, ethyl 2-chloroacetoacetate, Fe3O4 nanoparticles, green synthesis

Abstract

Magnetic Fe3O4 nanoparticles as a heterogeneous catalyst were found to be efficient for the synthesis of a series of pyrrole and indole derivatives using three-component reactions of primary amines, 1,3-dicarbonyl compounds, and activated acetylenic compounds under solvent-free conditions at room temperature. The present protocol offers the advantages of clean reaction, short reaction time, high yield, easy purification, and affordability of the catalyst.

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Published

2016-06-02

Issue

Vol. 52 No. 5 (2016)

Section

Original Papers