A NOVEL METHOD FOR THE SYNTHESIS OF PYRIMIDO[1,2-<i>a</i>]BENZIMIDAZOLES

Authors

  • Дмитрий Ю. Вандышев Voronezh State University
  • Хидмет С. Шихалиев Voronezh State University
  • Анна В. Коконова Voronezh State University
  • Андрей Ю. Потапов Voronezh State University
  • Мария Г. Колпакова Voronezh State University
  • Артем Л. Сабынин Voronezh State University
  • Федор И. Зубков People's Friendship University of Russia

DOI:

https://doi.org/10.1007/3165

Keywords:

N-arylitaconimides, 1, 2-diaminobenzimidazole, methypyrrolidine-2, 5-dione, pyrimido[1, 2-a]benzimidazole, polynucleophiles

Abstract

Condensation of 1,2-diaminobenzimidazole with N-arylitaconimides was studied. It was found that 2-(10-amino-N-aryl-2-oxo-2,3,4,10-tetrahydropyrimido[1,2-a]benzimidazol-3-yl)acetamides were formed in the course of this reaction upon brief heating to reflux of the reagent mixture in 2-propanol in the presence of catalytic amounts of acetic acid.

Authors: Dmitriy Yu. Vandyshev*, Khidmet S. Shikhaliev, Anna V. Kokonova, Andrei Yu. Potapov, Maria G. Kolpakova, Artem L. Sabynin, Fedor I. Zubkov

 

 

Author Biographies

Дмитрий Ю. Вандышев, Voronezh State University

Хидмет С. Шихалиев, Voronezh State University

Анна В. Коконова, Voronezh State University

Андрей Ю. Потапов, Voronezh State University

Мария Г. Колпакова, Voronezh State University

Артем Л. Сабынин, Voronezh State University

Федор И. Зубков, People's Friendship University of Russia

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Published

2016-07-18

Issue

Vol. 52 No. 7 (2016)

Section

Original Papers