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A NOVEL METHOD FOR THE SYNTHESIS OF PYRIMIDO[1,2-a]BENZIMIDAZOLES

Дмитрий Ю. Вандышев, Хидмет С. Шихалиев, Анна В. Коконова, Андрей Ю. Потапов, Мария Г. Колпакова, Артем Л. Сабынин, Федор И. Зубков
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Abstract


Condensation of 1,2-diaminobenzimidazole with N-arylitaconimides was studied. It was found that 2-(10-amino-N-aryl-2-oxo-2,3,4,10-tetrahydropyrimido[1,2-a]benzimidazol-3-yl)acetamides were formed in the course of this reaction upon brief heating to reflux of the reagent mixture in 2-propanol in the presence of catalytic amounts of acetic acid.

Authors: Dmitriy Yu. Vandyshev*, Khidmet S. Shikhaliev, Anna V. Kokonova, Andrei Yu. Potapov, Maria G. Kolpakova, Artem L. Sabynin, Fedor I. Zubkov

 

 


Keywords


N-arylitaconimides; 1,2-diaminobenzimidazole; methypyrrolidine-2,5-dione; pyrimido[1,2-a]benzimidazole; polynucleophiles

Full Text: PDF (Russian) Supplementary File(s): Supplementary information (738KB)


 

 

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