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REACTION OF α-TETRALONE, 1Н-TETRAZOL-5-AMINE, AND AROMATIC ALDEHYDES UPON MICROWAVE IRRADIATION – A CONVENIENT METHOD FOR THE SYNTHESIS OF 5,6,7,12-TETRAHYDROBENZO[h]TETRAZOLO[5,1-b]QUINAZOLINES

Григорий П. Кантин, Михаил Ю. Красавин
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Abstract


A multicomponent reaction between α-tetralone, 1Н-tetrazol-5-amine, and aromatic aldehyde, occurring upon microwave irradiation in acidic medium at 130°С, led to the formation of previously unknown 7-aryl-5,6,7,12-tetrahydrobenzo[h]tetrazolо[5,1-b]quinazolines in 5–52% yields.

Authors: Grigory P. Kantin, Mikhail Yu. Krasavin

 


Keywords


aldehydes; tetralone; 1Н-tetrazol-5-amine; Biginelli reaction; microwave irradiation; multicomponent reactions

Full Text: PDF (Russian) Supplementary File(s): Supporting information (497KB) Supporting information (1MB)


 

 

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